VLVbio was established in 2013 in Stockholm Sweden, havin
g been granted exclusive rights to a unique apoptosis marker for keratin 18 (K18) expressing cells of epithelial origin. We strive to co
ntinuously acquire and develop novel intellectual property from the academic research and healthcare market for the detection and quantification of different forms of cell death in normal or pathophysiological circumstances.
M30 Apoptosense® ELISA
M30 Apoptosense® ELISA is our best selling product and is a unique tool for reliable and reproducible quantitative detection of apoptosis of human, epithelial keratin 18 positive cells. Optimal applications fields for this kit are Hepatology, Oncology, Toxicology and more.
The M65® ELISA measures soluble keratin 18 (K18) released from dying cells and can be used to assess overall cell death (due to apoptosis and necrosis) of epithelial cells. The M65® ELISA is primarily intended to be used together with the M30 Apoptosense® assay, which specifically measures apoptosis. The M65® ELISA assay is registered as a medical device for in vitro diagnostic use in accordance with the CE-IVD directive.
M65 EpiDeath® ELISA
The M65 EpiDeath® ELISA represents the next generation of Keratin 18 biomarkers. It measures the same epitopes as the M65® ELISA, but with an improved measuring technique. The M65 EpiDeath® ELISA measures the co
ncentration of soluble Keratin 18 (K18, or Cytokeratin 18, CK18) in cell culture supernatants, serum and plasma. The K18 levels reflect the amount of total epithelial cell death, regardless of the cause of death (see background information).